• Isolators & Gloveboxes

Isolators & Gloveboxes

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Hosokawa Micron designs and builds a full range of Pharmaceutical Isolators including systems which are designed to achieve Occupational Exposure Limits (OELs) down to 10 ng/m3( 8hr TWA).

The development of increasingly potent and potentially toxic pharmaceutical products and chemicals has led to demands for increased operator protection from exposure to harmful dusts. In response Hosokawa Micron has pioneered the development of a range of high containment enclosures or Stott Isolators and Gloveboxes which create a physical barrier between the operator and the product. This enables ‘shirt sleeve operation’ without the need for Personal Protective Equipment.

The development of increasingly potent and potentially toxic pharmaceutical products and chemicals has led to demands for increased operator protection from exposure to harmful dusts. In response Hosokawa Micron has pioneered the development of a range of high containment enclosures or Stott Isolators and Gloveboxes which create a physical barrier between the operator and the product. This enables ‘shirt sleeve operation’ without the need for Personal Protective Equipment.

The development of increasingly potent and potentially toxic pharmaceutical products and chemicals has led to demands for increased operator protection from exposure to harmful dusts. In response Hosokawa Micron has pioneered the development of a range of high containment enclosures or Stott Isolators and Gloveboxes which create a physical barrier between the operator and the product. This enables ‘shirt sleeve operation’ without the need for Personal Protective Equipment.

Stott  Isolators are available for both manual and automated handling and processing procedures and are available in single units or multi-cell variants where defined barriers separate individual processes and offer complete operator safety and product integrity. They are ideal for such critical processes as milling, micronising, drying, dispensing and product pack off.

Integrated Containment Technology Hosokawa Micron’s Stott Isolators can be designed to contain either Hosokawa or third party processing equipment such as micronisers, tray dryers, granulators etc. Hosokawa Micron’s own range of equipment can be specially designed for installation inside an Isolator to offer a highly engineered, bespoke, contained processing solution.

Hosokawa Micron’s Stott Isolators can be designed to contain either Hosokawa or third party processing equipment such as micronisers, tray dryers, granulators etc. Hosokawa Micron’s own range of equipment can be specially designed for installation inside an Isolator to offer a highly engineered, bespoke, contained processing solution.

Mobile Isolators For companies looking for a lower cost alternative to the stainless steel isolator and shorter lead time for testing, trials or production processes the Mobile, plug and play, Isolators offer containment levels <1µg/m³.

  • Excellent internal visibility
  • Optional glove port positioning
  • Lightweight construction
  • Highly flexible in use as self-contained workstations.
  • Plastic bag canopy ‘single use’ variant available

Hosokawa Nuclear Containment Systems

The design of Hosokawa containment systems for the nuclear and associated industries is heavily influenced by our extensive experience of GMP containment system design for the Pharmaceutical industry. Primary considerations for such systems are operator protection, product protection, easy cleaning and good ergonomics. Integration of processing equipment in pharmaceutical containment systems is carried out so as to avoid contamination of drive systems and other parts which would be difficult to clean, to reduce the possibility of product cross contamination, reduce the hazard to personnel during maintenance and increase the reliability and lifespan of equipment. This is typically achieved by using through wall designs where the drive system is mounted in a technical enclosure which is isolated from the processing area.

In nuclear containment systems, similar design principles apply, crevices and areas where material can collect should be avoided and in some cases there may be a risk of reaching a critical mass of material which can become unstable and therefore all material brought into the system must be accounted for. Nuclear systems are typically designed for a lifespan of 25 years and the proper integration of process equipment as described above will help to reduce maintenance and increase reliability. If equipment is contaminated with radioactive material it cannot simply be cleaned and removed from the containment as with pharmaceutical systems. Class I nuclear gloveboxes are designed to achieve a leak-tightness of better than 0.05% volume per hour, compared to our standard pharmaceutical standard of 0.5% volume per hour.

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