Single-use filling flexibility, from benchtop to production
For over 25 years, Flexicon Liquid Filling expertise has delivered the advantages of peristaltic filling and capping solutions to biopharmaceutical users as they scale-up from research to production. Now, with the launch of the company’s easy-to-validate, asepticsu™ single-use fluid path technology, simplicity and security is assured in all high purity, high accuracy liquid filling applications.
Flexicon peristaltic precision filling with asepticsu single-use technology increases flexibility and performance, while reducing risk and complexity, delivering significant added value when filling from less than 0.5ml to over 50ml.
Simplify the validation process
asepticsu is the preferred single-use alternative to traditional hard piped systems with piston pumps that require complex cleaning validation. Flexicon’s asepticsu technology, supported by a comprehensive validation pack, can save significant time, effort and cost in validating a new filling process. Shorter time to market, confident on-going validation compliance, and greater profits are the potential rewards for manufacturers, contract fillers, or R&D operators who standardise on asepticsu.
Remove risks of liquid contamination
Single-use technology is arguably the biggest growth area in aseptic processing, with quality engineers keen to ensure that systems are clear from any risk of contamination. Using the gamma-sterilised asepticsu single use fluid path, liquid does not contact any mechanical parts, permanent pipework or the external environment, so there is no risk of cross contamination. As a result, the requirement for cleaning validation is eliminated, offering simple and fast changeover for a variety of fills.
Ultimately, the combination of asepticsu and Flexicon peristaltic technology lowers the risk in all high purity, high accuracy filling applications.
Easy change-over between liquids
Flexibility of filling is vitally important and asepticsu ensures that changeover between batches can take place within minutes. Once the filling process is complete, asepticsu can simply be removed from the filling line. As a result, small batch production becomes easier and more efficient. As smaller lot sizes are very much the industry trend, this new technology represents best practice for all aseptic filling applications.
Exceptional filling accuracy
At the heart of asepticsu is Accusil® platinum-cured silicone tubing engineered specifically for accurate dispensing using Flexicon filling equipment. Delivering impressive filling accuracy of ±0.5%, Accusil prevents costly over or underfilling of vaccines, liquids for lyophilisation, diagnostic liquids or biotech products, where accuracy is of utmost importance to both    end-user and manufacturer.
Accusil is engineered for post-irradiation dispensing stability and manufactured in our own ISO 14644-1 Class 7 cleanroom under tight tolerances. This innovative tubing is post-cured for lowest extractables and features indelible, laser-etched lot data.
Flexible, reliable supply
A diverse range of Flexicon asepticsu single-use fluid path options help users meet their different requirements from pre-clinical trials to full production scale. For instance, a range of six tube sizes and bag sizes from 1 to 10 litres, accommodate fill requirements from less than 0.5 ml to over 50ml. Various filling nozzle options are available to fill above or inside the vial, preventing dripping between fills and minimising foaming or splashing.
Users keen to take advantage of the benefits offered by asepticsu, but who currently do not have peristaltic dispensers on their filling lines are advised to contact Flexicon Liquid Filling for a free consultation. Existing filling lines can be modified or integrated with peristaltic filling technology prior to an audit, or simply if a customer wants to make a filling process more flexible.
Watson-Marlow Fluid Technology Solutions
- 01326370370
- info@wmftg.co.uk
- https://www.wmfts.com/
- Bicklandwater Road, Falmouth Business Park, Falmouth, Cornwall, TR11 4RU GB
About us
Watson-Marlow Fluid Technology Group (WMFTG) peristaltic tube and hose pumps meet requirements including: value for money; low cost of ownership; reliability and ease of maintenance to the food and beverage, chemical, pharmaceutical, mining and many other industries.
We demonstrate how pumps deliver significant process efficiencies over the lifetime of the equipment. Whether performing flavouring addition in food processing, chemical metering in water treatment or mineral recovery, we have a solution which can cut pump downtime and reduce costs through higher accuracy metering and transfer. WMFTG has dedicated application engineers available to help customers make the right pump and tubing choice from a range providing microlitres per minute to 80 cubic metres per hour flow rates.
The only part of the pump to come into contact with the product is the tube or hose. This means there are no seals or valves that can wear or fail. Replacing the tube or hose can be performed quickly and safely. Peristaltic pump benefits include:
Total fluid containment with no seals No ancillaries Handle viscous and abrasive slurries and sludge Self-priming capability Dry running without damage to the pump In addition to their range of positive displacement pumps, Watson-Marlow Fluid Technology Group has added PTFE-lined chemical and industrial hoses to their range. Aflex hoses are reinforced to withstand the most severe conditions and use.
Where we supply to
Europe, Africa, Asia, Australia, South America, North America
Industries we supply to
Automation, Chemicals, Consultants, Components Electronics, Energy and Power, Food and Beverage, Glass Ceramics Cement, Metals and Minerals, OEM, Paper and Pulp, Pharmaceutical Cosmetics Toiletries, Plastics and Rubber, Recycling, Textiles, Tobacco, Water and Wastewater
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