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Fluids Handling

Sterile Valve Application

Eye Ointment Production Line

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Application

In the production of eye ointment, it is vitally important to ensure that the components are mixed correctly and, above all, that they are sterile. For this purpose, the plant includes a vacuum process system including two sequentially switched mixing tanks with speed-controlled agitators. Their task is to mix the fully automated process media gently at a constant pressure and to emulsify them. In order to avoid boundary layers during the mixing process and to guarantee constant and even consistency, the mixture is withdrawn from the pre-mixer and fed into the final mixer via a sophisticated pipe system. This ensures that no concentration gradients occur and that the eye ointment is perfectly mixed and to a constant high quality. After preparation is complete, the eye ointment is passed on to storage containers.

Plant Design

GEMU M600 valve block with 650 BioStar actuators

GEMÜ M600 valve block with 650 BioStar actuators and 1236 switchboxes
(showing SIP steam inlet to block)

For controlling the sterile media, stainless steel aseptic multi-port diaphragm valve blocks were selected for feeding the media in the bypass pipe system and for removal of the final product. Cleaning and sterilisation of the whole production line is also integrated into the block valves’ functionality with SIP (Steam in place) valves machined into the blocks. This means that unnecessary deadlegs between the valves can be avoided and welded joints saved. A further special feature is the fully automatic control/monitoring system using fieldbus supported switchboxes.

Solution

GEMU BioStar 650, 653 & 654

From left to right: GEMÜ BioStar 650, 653 & 654.

All valve functions are combined into the compact multi-port valve blocks (GEMÜ-M600) based on diaphragm valves. The valve blocks are individually designed to meet all requirements during the system planning phase. The GEMÜ BioStar range of actuated and manual valves, such as GEMÜ 650, 653, and 654 are used to operate the valves. All BioStar valves are designed according to Good Manufacturing Practice (GMP) for use in a sterile environment. On top of their safe function, their design also ensures that they can be easily cleaned externally. GEMÜ 1236 switchboxes are mounted on the GEMÜ 650 pneumatic actuators. The current position of the valve is displayed via high visibility LEDs and fed back to the plant control system.

Technical Details:

GEMÜ 650 
GEMÜ 653
GEMÜ 654

GEMÜ Valves Ltd
Standard Package

GEMU Valves Ltd

About us

GEMÜ is a world leading manufacturer of valves, measurement and control systems for liquids, vapours and gases, especially when it comes to solutions for sterile applications. The GEMÜ Group currently employs over 1900 members of staff worldwide.

Manufacturing is carried out at six manufacturing sites across Germany, Switzerland, China, Brazil, France and the USA. The Group is active on all five continents with 27 subsidiaries and has a large distributor network in more than 50 countries

With the increasing requirements for process engineering, we offer a wide range of products providing solutions for a broad spectrum of customer groups, such as:

Specialising in all of the processes involved in the pharmaceutical, biotechnology, cosmetics, food and beverage industries. Application brochure: Solutions for the pharmaceutical, foodstuffs and biotechnology industries.

Specialising in industrial water treatment, chemicals, processing industry, surface finishing, power generation and environmental engineering. Application brochure: Solutions for industrial applications.

Focusing on valves for the production of semiconductors and microchips, photovoltaic systems and batteries,Ā and ultra-high-purity chemicals. Application brochure: Solutions for microelectronics, semiconductors and battery production.

  • Service

Training courses for service and maintenance personnel, repair services and the commissioning of GEMÜ products directly at the customer's site.

 

GEMÜ GB is based in Warrington providing product sales and technical support. Our product quality, application knowledge and broad range of services, make us a market leader in our field within the UK.

 

GO GREEN & PAPERLESS!
New PDF product catalogues are available for download.
Click on the links below to download the new product catalogues. We recommend you open the links for download usingĀ Google ChromeĀ browser.

Product Catalogue for the Pharmaceutical, Foodstuff and Biotechnology Industries
Product Catalogue for Industrial Applications
Product Catalogue for Semiconductor Production

Follow our social media accounts to stay up to date with our latest GEMÜ GB news, events and industry insights: LinkedIn; Twitter; Instagram; Facebook; YouTube.

Where we supply to

UK Ireland

Industries we supply to

Chemicals, Food and Beverage, Pharmaceutical Cosmetics Toiletries, Water and Wastewater

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