Using uniaxial powder testing to optimise high shear wet granulation
Uniaxial Unconfined Yield Strength (uUYS) can be used to assess and rank powder flowability for a wide range of powder handling processes in various industries, including Chemical, Food, Construction and Pharmaceutical.
Uniaxial testing first involves the construction of a powder column at a given Major Principal Stress (MPS or σ1), the confining sleeve is then removed, before the freestanding column of material is fractured. The force required to break the column informs on the uUYS (σC) of the powder. The UPT also allows bulk powder properties such as density and compressibility to be determined.
Consolidation studies can also be conducted in a range of environments using an off-instrument Consolidation Station. Samples can be consolidated for extended periods of time, at a specific humidity and/or temperature.
Our new application note “Uniaxial Powder Testing for Optimising High Shear Wet Granulation” presents a study using the Uniaxial Powder Tester (UPT) to characterise a range of pharmaceutical blends and the corresponding granulates to illustrate how uUYS values can clearly differentiate between the formulations and quantify the impact of the granulation process conditions.
Freeman Technology
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- info@freemantech.co.uk
- https://www.freemantech.co.uk
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About us
Freeman Technology specialises in systems for measuring the flow properties of powders and has nearly 20 years' experience in powder flow and powder characterisation.
The company invests significantly in R&D and applications development, and provides detailed know-how to support its range of products. Expert teams guide and support users around the world in addressing their individual powder challenges, focusing on delivering the most relevant information for the process. The result is world-leading solutions for understanding powder behaviour - in development, formulation, scale-up, processing, quality control, or anywhere that powders have a role.
Freeman Technology’s solutions include the FT4 Powder Rheometer®, a uniquely universal powder tester, and the Uniaxial Powder Tester, a complementary tool for quick and robust powder assessment. Systems are installed around the world in the chemical, pharmaceutical, toners, foods, powder coatings, metals, ceramics, cosmetics, and many other industries. They deliver data that maximise process and product understanding, accelerating R&D and formulation towards successful commercialisation, and supporting the long term optimisation of powder processes.
Founded in 1989 as a developer of automated testing systems for materials characterisation, the company has focused exclusively on powders since the late 1990s and in 2018 became part of Micromeritics Instrument Corporation. The company’s R&D, manufacturing and commercial headquarters are in Gloucestershire, UK, with operations and distribution partners in key global territories. In 2007 the company received the Queen’s Award for Enterprise in Innovation and in 2012 the Queen’s Award for Enterprise in International Trade.
Where we supply to
UK Ireland, Europe, Africa, Asia, Australia, South America, North America
Industries we supply to
Chemicals, Food and Beverage, Pharmaceutical Cosmetics Toiletries
