Key points
Application
The plant is used for manufacturing liquid pharmaceutical products and consists of raw material supply, preparation and mixing of liquids and cleaning. Three tanks are available for the preparation of liquids (2 x 1000 l and 1 x 2000 l). The tanks are pressure and vacuum resistant from -1 bar to +3 bar.
Each tank is equipped with a separate heating/cooling system. The prepared products are mixed in 3 different mixing tanks with contents of 2000 l each or in movable containers. The plant is designed according to Good Manufacturing Practice (GMP) and qualified.
Plant design
The tanks, all other parts of the plant and the pipelines are made from stainless steel 1.4404 316 L. All medium wetted surfaces are Ra 0.8 µm. The plant is intrinsically safe. The switch gear cubicles for the control system of the plant are located in a non-hazardous area. For the operation of the automated plant there is a touch panel in the hazardous area and a PC in the control centre.
The PC visualises all the operating sequences via WINCC. PM-Batch and PM-Quality are used to make recipes, manufacture preparations, generate preparation and cleaning protocols.
The raw materials are DI water, ethanol and isopropanol which are directly batched from the raw material storage tanks, solid and other liquid components are batched by means of vacuum suction from drums.
Solution
The DI water, ethanol and isopropanol supply is controlled by GEMÜ 688 diaphragm valves with pneumatic two-stage actuators. The end positions are monitored by means of GEMÜ 1231 electrical position indicators with proximity switches according to NAMUR.
The GEMÜ 688 two-stage batch valve in conjunction with a totalizer enables exact batching of the raw materials and shortest possible batch times. GEMÜ 612/673 manual diaphragm valves and GEMÜ 687 pneumatic valves are also used in this application.
GEMÜ 673 and 687 valve bodies can be lined with high-quality polypropylene (PP), fluoroplastics (PFA), as well as soft and hard rubber lining making the valves highly versatile and robust when used in Lined Pipe Systems, when containing and transporting active pharmaceutical ingredients (API’s) in their raw chemical state.
For more information, click here.
Tel: 01925 824044
Email: enquiries@gemu.co.uk
Web: www.gemu.co.uk
GEMU Valves Ltd
- +441925824044
- customer.support@gemu.co.uk
- http://www.gemu.co.uk
- 10 Olympic Way Birchwood Warrington Cheshire WA2 0YL GB
About us
GEMÜ is a world leading manufacturer of valves, measurement and control systems for liquids, vapours and gases, especially when it comes to solutions for sterile applications. The GEMÜ Group currently employs over 1900 members of staff worldwide.
Manufacturing is carried out at six manufacturing sites across Germany, Switzerland, China, Brazil, France and the USA. The Group is active on all five continents with 27 subsidiaries and has a large distributor network in more than 50 countries
With the increasing requirements for process engineering, we offer a wide range of products providing solutions for a broad spectrum of customer groups, such as:
Specialising in all of the processes involved in the pharmaceutical, biotechnology, cosmetics, food and beverage industries. Application brochure: Solutions for the pharmaceutical, foodstuffs and biotechnology industries.
Specialising in industrial water treatment, chemicals, processing industry, surface finishing, power generation and environmental engineering. Application brochure: Solutions for industrial applications.
Focusing on valves for the production of semiconductors and microchips, photovoltaic systems and batteries, and ultra-high-purity chemicals. Application brochure: Solutions for microelectronics, semiconductors and battery production.
- Service
Training courses for service and maintenance personnel, repair services and the commissioning of GEMÜ products directly at the customer's site.
GEMÜ GB is based in Warrington providing product sales and technical support. Our product quality, application knowledge and broad range of services, make us a market leader in our field within the UK.
GO GREEN & PAPERLESS!
New PDF product catalogues are available for download.
Click on the links below to download the new product catalogues. We recommend you open the links for download using Google Chrome browser.
Product Catalogue for the Pharmaceutical, Foodstuff and Biotechnology Industries
Product Catalogue for Industrial Applications
Product Catalogue for Semiconductor Production
Follow our social media accounts to stay up to date with our latest GEMÜ GB news, events and industry insights: LinkedIn; Twitter; Instagram; Facebook; YouTube.
Where we supply to
UK Ireland
Industries we supply to
Chemicals, Food and Beverage, Pharmaceutical Cosmetics Toiletries, Water and Wastewater
-
GEMU Butterfly Valve Production Centre
-
How to replace diaphragm code 5E on the GEMÜ 650 BioStar
-
GEMÜ 490: Butterfly valve for controlling corrosive media
